User blog comment:Drakan95/Ötzi vs Fred Flintstone. Epic Rap Battles: Cartoons vs History. Season 1 Premiere/@comment-5393732-20150504025441

Pinkie Pie vs P!nk

Fat Albert vs Santa Claus

Clone High vs the actual Abe Lincoln, Gandhi, Joan of Arc, Cleopatra, and JFK (bpf)

Dr. Doofenshmirtz vs Dr. Evil

WALL-E vs HAL

Cruella DeVille vs Catwoman

KND vs Spy Kids

Homestar Runner vs Homestuck (unless Homestuck counts as a cartoon)

Courage vs Cujo

Beavis and Butthead vs Bill and Ted

The Tick vs Ant-Man

The Simpsons vs The Brady Bunch

Daria vs Juno MacGuff

Shrek vs The Hulk