User blog comment:Drakan95/Piccolo vs Martian Manhunter. Epic Rap Battles: Cartoons vs History. Season 2/@comment-35597744-20180608201821

This was great! I would probably give this one to Piccolo for a lot of his lines such as the schoolgirl one.

Now for the obligatory suggestions:

Speed Racer vs. The Stig or Dale Earnhardt (Racers)

Ame and Yuki (Wolf Children) vs. Remus and Romulus (All of them had a childhood involving wolves. Humans who can become wolves vs. humans raised by a wolf.)

Wallace and Gromit vs. Rube Goldberg (Finally found an opponent for Wallace and Gromit. Connection being that they all make wacky contraptions.)

Voldemort vs. The Lich King (Diabolical undead beings who are the main antagonists of their respective series.)

Samurai Jack vs. Okita Sōji (Samurais) or maybe Marty McFly (Both were sent to a different time period and had to find a way back to their right time.)