User blog comment:Drakan95/Michael Bay vs Wile E. Coyote. Epic Rap Battles: Cartoons vs History/@comment-5264252-20150613021506/@comment-25263388-20150613023421

However, you're using batman, Superman and Wonder Woman, who are the three biggies of the Justice League, and DC is all one universe (whilst still 52 :P) so they come in one universe, but it's very clear that all (or most) mangas/animes are set in independent universes. S, B and WW have a few joint series, World's Finest and JL (even if World's Finest is over, which I suspect it is)

And I'd say Goku, Piccolo and Krillin vs Superman, Supergirl and Steel, since both Steel and Krillin are weak (relatively) but tactical humans and the others are aliens who are just OP.

Plus, Krypto would probably be used as a cartoon

and Nightwing and Robin would make more sense then Batgirl.